The study evaluated the impact of L. mesenteroides on colon cancer cells’ viability and apoptotic marker transcription (caspase 3 (CASP3), caspase 7 (CASP7), caspase 8 (CASP8), cytochrome c (CYCS), BCL-2 apoptosis regulator (BCL-2)), as well as its influence on PD-L1 transcription and protein levels. Here, CASP3 is linked to colonic neoplasm.