As the lymph nodes play an essential role in cross-presenting antigen to T cells and initiating T cell killing of tumors, we also assessed the maturation and activation of DCs in dLNs after zebularine treatment in B16F10 tumor-bearing wild-type, Cgas-/-, Sting gt/gt, and IFNAR1-/- mice. The gene discussed is CGAS; the disease is neoplasm.