HLA-A and melanoma: We also observed by flow cytometry that zebularine promoted the upregulation of tumor cell surface antigen H-2Kb/H-2Db in B16F10-melanoma (Fig. 6f, g) and MC38-colorectal (Fig. 6h, i) cell lines in a dose-dependent manner, as well as HLA-A/B/C expression in the A375-melanoma cell line (Fig. 6j).