IFNG and Hypoalbuminemia: Interestingly, our findings demonstrate that the prognostic capacity of hypoalbuminemia in this context is independent from other established biomarkers (including: elevated LDH, low IFN-γ signature RNA expression, and low TMB) and prognostic clinical characteristics (including: age, ECOG PS, brain or liver metastases, treatment line, mono/combi-treatment).