Our analyses revealed that compared to the group of patients with normal LDH and normal albumin as reference (n = 38), individuals with hypoalbuminemia and high or low LDH exhibited significantly shorter survival OS (albumin < LLN + LDH ≥ 2ULN, Cox P = 0.0232, n = 14; albumin < LLN + LDH < 2ULN, Cox P = 0.0329, n = 21). The gene discussed is ALB; the disease is Hypoalbuminemia.