Compared to the subgroup of patients with both an normal LDH and normal albumin (n = 102), we observed significantly shorter OS and PFS for patients with hypoalbuminemia and normal LDH (albumin < LLN + LDH < 2ULN, OS: Cox P = 3.29e−6, PFS: Cox P = 1.06e−5, n = 11; Fig. 3c,d), and particularly poor survival in the small subset of patients with hypoalbuminemia plus a high LDH (albumin < LLN + LDH ≥ 2ULN, OS: Cox P = 3.04e−4, PFS: Cox P = 2.3e−05, n = 4; Fig. 3c,d). Here, ALB is linked to Hypoalbuminemia.