MTHFR and Stroke: In stroke patients, fibrin Absmax was associated with a different set of variables that included pCysGly (β = 0.17, P = 0.017), pMet (β = − 0.18, P = 0.009), and three other variables: MTHFR A1298C (β = 0.18, P = 0.009) and CBS T833C 844ins68 (β = 0.13, P = 0.049) polymorphisms, and fibrin CLT (β = 0.31, P = 0.000); adjusted R2 was 0.18, P = 0.000 (Table 4).