The latter is supported by the fact that PGLYRP1 KO cells efficiently formed tumours in immunocompromised mice but not in immunocompetent animals, and in vitro, PGLYRP1 KO cells are more susceptible to T-cell-mediated killing and macrophage phagocytosis than WT and OE cells. This evidence concerns the gene PGLYRP1 and neoplasm.