Although ID11 KO cells grew significantly slower than WT cells, tumours did not show significant diferences in final average weight and volume, which was replicated with the ID95-derived cell lines, suggesting that PGLYRP1 does not impair tumour initiation/stemness and that adaptive immune cells and fully functional innate immune cells were likely responsible for impeding KO cell growth in the immunocompetent setting (online supplemental figure S3G). The gene discussed is PGLYRP1; the disease is neoplasm.