PGLYRP1 and neoplasm: Moreover, PGLYRP1 exposure also induced the expression of Camp, which has been shown to activate CSCs,35 reduced the expression of Tnf (online supplemental figure S5G) and increased MΦ migration (online supplemental figure S5H), despite no significant effects on MΦ infiltration in PGLYRP1 OE tumours in vivo.