ERC2 and obesity due to melanocortin 4 receptor deficiency: Others among the top 10% high-scoring genes with an unknown role in the context of obesity include ERC2 (23.8), ZNF131 (23.8), NLGN1 (22.8), MLTT10 (22.8), RERE (22.8), and PDCH9 (22.8).