The signal pathways involved in stroke are PI3K/Akt signaling pathway, phosphatase and tensin homolog signaling pathway, death-associated protein kinase 1 signaling pathway, neuronal nitric oxide synthase signaling pathways, hypoxia-inducible factor signaling pathway, nuclear factor E2-related factor 2 signaling pathway, casein kinase 2 signaling pathway, mTOR-related signaling pathways, and p53-mediated apoptotic pathway [24–32]. The gene discussed is AKT1; the disease is stroke disorder.