Using bioplex assays testing 30 different cytokines in patient plasma (Supplementary Table 1), we observed that 10 cytokines were significantly more present in the plasma of GBM patients than in controls, including inflammatory signals like CXCL10, GM-CSF, IL-6, Eotaxin, and IL-1rα (Fig. 1L and Supplementary Fig. 1C). The gene discussed is IL6; the disease is glioblastoma.