The research demonstrated that miR-142-3p directly targeted the 3 ‘untranslated region of HMGA2, thereby down-regulating HMGA2 protein and mRNA expression levels, inhibiting BC cell dryness and reducing apoptosis, suggesting that HMGA2 is a direct target of miR-142-3p (Mansoori et al. 2021). This evidence concerns the gene HMGA2 and breast cancer.