CD274 and invasive carcinoma: In respect to histologic subtype, invasive carcinoma of no special type showed an increase in the number of PD-L1-positive immune cells after NAC (3.1% to 5.9% on average; p = 0.022); however, metaplastic carcinoma did not show an increase in the number of PD-L1-positive immune cells after NAC (1.5% to 0.6% on average; p = 0.531).