IL24 and neoplasm: Notably, other than the effects on wound healing observed on a receptor-dependent manner (He and Liang, 2010; Kolumam et al., 2017; Liu et al., 2023), IL-24 has been revealed in promoting tumor cell-specific apoptosis, maintaining Th17 homeostasis and ER homeostasis through a receptor-independent way (Chong et al., 2020; Sauane et al., 2004; Sie et al., 2022; Wang et al., 2020).