TGFB1 and neoplasm: Anti‐inflammatory cytokines and immune‐suppressive molecules produced during the polarization of M2 macrophages, such as anti‐inflammatory cytokine IL‐10 and anti‐inflammatory cytokine TGF‐β, suppress the activity of immune cells such as T cells and natural killer cells, weakening their attack against tumour cells and promoting immune escape of the tumour.