When we compared the severe myocarditis patients (n = 21) versus non‐severe myocarditis patients (n = 14) (Table 4), they presented higher cTnI levels (median of 63.9‐fold the upper limit vs. 8.8‐fold, p = 0.013), higher NT‐proBNP levels (median of 5.1‐fold the upper limit vs. 1.2‐fold, p = 0.031), higher CK levels (median of 9.1‐fold the upper limit vs. 0.4‐fold, p = 0.018), higher CK‐MB levels (median of 6.8‐fold the upper limit vs. 1.3‐fold, p = 0.026), and higher NLR levels (median of 11.4‐fold the upper limit vs. 6.8‐fold, p = 0.016) after ICI treatment. The gene discussed is NPPB; the disease is myocarditis.