Longati et al. discovered the mRNA expression ratios of glucose transporter 1 (GLUT1 is the predominant glucose transporter in many types of cancer) and lactate dehydrogenase (LDH; the enzyme responsible for lactate production) on PANC1 pancreatic cancer cells cultured in 2D/3D were approximately 3.5 and 7.5, respectively. This evidence concerns the gene SLC2A1 and cancer.