These variables include age, medical comorbidities (hypertension, CHD, tumor), SBP, use of statins, use of antiplatelet drugs, laboratory tests (Hcy, Cys C, UA, CREA, UREA, h-CRP, TC, TG, HDL, LDL, TP, ALB, BNP, HbA1C, PLT; Table 2). The gene discussed is NPPB; the disease is hypertensive disorder.