LRRK2 and Parkinson disease: P-α-syn deposits were detected in the subepidermal plexus, dermal nerve bundles, arrector pili muscles, and blood vessels (Figure 1) of three PD patients with the CHCHD2 T61I mutation (75%), 11 PD patients with LRRK2 mutations (78.57%), and two patients with GBA mutations (40%; Table 3).