The deregulation of Aurora A kinase is shown to induce mitotic arrest followed by apoptosis as well as severe mitotic abnormalities that result in selective lethality for many types of solid and hematological malignancies (Du and Hannon, 2004; Harrington et al., 2004; Cheung et al., 2009; Perez Fidalgo et al., 2009; Moore et al., 2010; Malumbres and Perez de Castro, 2014). This evidence concerns the gene AURKA and hematologic disorder.