SOD1 and carcinoma of esophagus: In lung carcinoma, MT1M overexpression inhibits cell viability and migration through MDM2/p53 signaling, and in esophageal carcinoma, it inhibits the epithelial–mesenchymal transition (EMT) through the SOD1/PI3K signaling axis (Xu et al., 2020; Li et al., 2021).