BCAM and neoplasm: This combination achieved a 2-fold highertumor-to-kidney ratio compared to both the 15-mer ZHER2:342-HP15:[177Lu]Lu-HP18 probe pair and the first-generation15-mer ZHER2:342-HP1:[177Lu]Lu-HP2 probes.29 Notably, the kidney uptake for [177Lu]Lu-HP16 (6 ± 1% ID/g) was significantly lower than that of[177Lu]Lu-HP18 (12 ± 2% ID/g) and [177Lu]Lu-HP2(10 ± 2% ID/g), while the tumor uptake values ranged from 19to 24% ID/g, with no significant differences observed between thedifferent secondary probes.