TTR and cardiac amyloidosis: Cardiac amyloidosis should be actively suspected in patients with ECV >40%.7 Approximately 23% of patients are diagnosed with wild-type transthyretin cardiac amyloidosis (ATTR-CA) based on incidental findings detected during imaging examinations, such as echocardiography and bone scintigraphy.8 Performing CT-ECV simultaneously with coronary CTA and examining patients with high CT-ECV values may lead to an early diagnosis of cardiac amyloidosis; however, this hypothesis has not been fully evaluated.