Univariate analysis performed to identify the predictors of CT-ECV ≥ 35% identified older age; male sex; history of diabetes mellitus; previous revascularization; estimated GFR; hs-cTnT, BNP, and sodium levels; LV diastolic diameter; LV systolic diameter; IVST; LV posterior wall thickness; LVEF; and E/e′ as predictors of CT-ECV ≥ 35%. This evidence concerns the gene NPPB and diabetes mellitus.