As evidenced by the aforementioned study involving type 2 diabetes mellitus [10], Me4FDG may be able to be potentially employed to investigate the contribution of the renal system to obesity-related diseases, as Me4FDG is able to determine the threshold of renal glucose reabsorption, a process carried out exclusively by the two transporters SGLT1 and SGLT2. The gene discussed is SLC5A2; the disease is obesity due to melanocortin 4 receptor deficiency.