We quantified the concentrations of CXCL1, CXCL8 and CCL15 in serum samples collected from patients with cStage IーIII CRC (n = 94), and then classified them into 4 groups based on CXCL1 or 8 level and CCL15 level (Fig. 1c). Here, CXCL8 is linked to colorectal carcinoma.