We also observed associations between 131 proteins and risk of liver cancer that included IGFBP7 and IGFBP3 [1.65 (1.48–1.84) and 0.46 (0.39–0.54), respectively], and 51 proteins and risk of kidney cancer, such as HAVCR1 and ESM1 [2.88 (2.55–3.24) and 1.84 (1.55–2.19)]. This evidence concerns the gene ESM1 and liver cancer.