Other transcripts upregulated in CD5L− peritoneal cells, including Osm, Il18bp, Ripk1, Nub1, Tlr2, Stat1, Irf1, Nfkb1, Pik3r5, or their coding proteins (Fig. 2d), were already associated with sepsis severity49–57. The gene discussed is PIK3R5; the disease is Sepsis.