CD8A and infection: •Entry through avB3 integrin [151] through clathrin dependent endocytosis [123]. Viral binding to cd55 permits infection from apical surface possibly by altering junctional complexes and increasing permeability [151]•Can infect and primarily replicate in endothelia, especially those in the kidney [123, 132]•Monocytes/macrophages [132]•CD8+ T cells may be susceptible to infection [152]