The RNAseq data on whole blood (EGAS00001004503) of 10 controls, 20 severe and 19 mild COVID-19 patients showed log2 fold change in NLRP3 (1.25), CASP-1 (1.21) and IL-1β (1.38) in severely infected patients only. Here, NLRP3 is linked to COVID-19.