DXO and infection: Next, we checked whether the depletionof the NAD cap on U1 RNA in HIV-1-infected cells is not caused bythe upregulation of DXO or Nudt12 upon infection; however, Westernblot and RT–qPCR analysis showed that the levels of DXO aresimilar in the control and HIV-1-infected cells (see Figures S8A and S8B).