Expressions of the 3 LXR target genes — ABCG1, ABCA, and MYLIP — were strongly correlated with each other and PC2CMTN; thus, their gene effects on prediabetes/T2D were not independent from each other, and can be represented by PC2CMTN, reflecting an aberrant LXR/ABCG1-ABCA1-MYLIP pathway (LAAMP) rather than an isolated effect of each gene alone. The gene discussed is ABCG1; the disease is prediabetes syndrome.