In addition, visiting the human genome database (105) and looking at the currently discovered genetic variants associated with migraine, in order of relevance of the variant to migraine, the first three most relevant variants out of 3,866 to date are the ATP1A2 (Na+/K+/ATPase Subunit Alpha 2), CACNA1A (Calcium Voltage-Gated Channel Subunit Alpha A), and SCN1A (Sodium Voltage-Gated Channel Alpha Subunit 1). The gene discussed is CACNA1A; the disease is migraine disorder.