PDE6B and retinitis pigmentosa 1: The rd10 mouse model recapitulates a human form of RP in which a missense mutation in the catalytic phosphodiesterase-6 β subunit (PDE6β) disrupts rod photoreceptor function and causes progressive rod death beginning at ages P16–18 (Barhoum et al., 2008; Hamel, 2006; Narayan et al., 2016; O’Neal & Luther, 2023; Stasheff et al., 2011; Yu et al., 2020), followed closely by cone degeneration (Barone et al., 2014; Narayan et al., 2016; Punzo et al., 2009).