Thus, these results altogether suggest CBX might exert its functions while regulating proinflammatory and anti-inflammatory cytokines, as shown in the MS model in the initial phase, and through glial and perivascular PDGFR positive cells, hindering perivascular fibrosis, oxidative stress, and excitotoxicity in the healing phase (Shijie et al., 2009; Hellmich et al., 2013; Thakur and Nehru, 2015). The gene discussed is CBX1; the disease is myeloid sarcoma.