POMC and neoplasm: Further multiple regression analysis revealed that age (1.094 [1.049–1.141], P<0.001) and tumor size (4.508 [2.370–8.576], P<0.001) were independent risk factors for 1-mg DST>1.8 ug/dL, and ACTH (0.967 [0.938–0.997], P<0.05) was a protective factor for it.