MOTIF analysis of DNA sequences within AR peaks identified a motif (E=2.7e-268) which mapped to both androgen receptor motif ANDR (E = 1.26e-2) (Figure 3B) and progesterone receptor motif PRGR (1.28e-6), and we have previously shown that the progesterone pathway is active in ovulatory PCOS patients (7). The gene discussed is AR; the disease is polycystic ovary syndrome.