From the WT1/AR merged peaks, 165 occupied H3K27ac enriched regions (22.9%, P-value < 0.001 one-sided Fishers exact test) (Figure 5B, Supplementary Table S4), implying that competitive binding of AR in WT1 binding regions affects putative enhancer activity in PCOS patients, resulting in aberrant gene regulation. The gene discussed is WT1; the disease is polycystic ovary syndrome.