Compared with to the low-stable group, patients in the high-stable and elevated-increasing groups were more likely to be older, current smokers, and have had a longer DM course and have higher levels of 2-h PG, HbA1c, NT-proBNP, uACR, and LVMI, while featuring a higher prevalence of hypertension and a lower proportion of β-receptor blocker treatment (p < 0.05) (Table 1). This evidence concerns the gene NPPB and Hypertension.