Functionally, Pin1 contributes to the acquisition of at least 10 of Hanahan and Weinberg’s cancer hallmarks: sustaining proliferative signaling, evading growth suppression, enabling replicative immortality, activating invasion and metastasis, inducing angiogenesis, avoiding immune destruction, deregulating cellular energetics, genomic instability, tumor-promoting inflammation, and evading apoptosis (Chen et al., 2018). Here, PIN1 is linked to cancer.