The von Willebrand Factor is named after Erik von Willebrand, a Finnish doctor who documented a family with a seemingly hereditary bleeding disease, now known as von Willebrand disease (VWD) (Peyvandi et al., 2011) and was able to differentiate this disorder from hemophilia, despite similar symptoms (Favaloro, 2014). This evidence concerns the gene VWF and von Willebrand disease (hereditary or acquired).