The enzymatic activity assay measuring the IAP ability to dephosphorylate pNPP in intestinal resection specimens showed a median (IQR) IAP activity in resection specimens of NEC patients of 49 (11–50) U/g of protein vs. 115 (26–211) U/g of protein in controls, P = 0.03 (see Table 2). Here, ALPI is linked to necrotizing enterocolitis.