CTLA4 and neoplasm: Indeed, blocking other inhibitory receptors on ILC1s for example cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), T cell Ig and ITIM domain (TIGIT) and T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) may similarly enhance ILC1 anti-tumour activity [63, 64].