Hamann et al. reported that the oxidative stress (OS)-related molecule CD163 is up-regulated in AAA, accompanied by up-regulation of the anti-OS TF NRF2 and its mediated HO-1, NQO-1, revealing the potential value of the CD163/NRF2-related pathway in the diagnosis of AAA (74). The gene discussed is CD163; the disease is triple-A syndrome.