IL6 and Kawasaki disease: The main cytokines responsible for inducing LRG1, TFN-α and IL-6, are elevated in the plasma of patients with Kawasaki disease, and a proteomic analysis of serum exosomes of patients with coronary artery aneurysms caused by Kawasaki disease showed upregulated LRG1 levels, although no causal link with pathology was shown (183).