The resulting selective cancer cell death via the induction of apoptosis and autophagy by OBP-702 increased the release of immunologic molecules including HMGB-1, ATP, and calreticulin, inducing immunologic cell death and resulting in OBP-702 restoring intraperitoneal anti-tumor immunity for PM, such as enhancement of CD8+ T cell infiltration into the tumor. This evidence concerns the gene CD8A and cancer.