However, as T cells co-expressing IL-10 with IFNγ or IL-17A are less pathogenic in MS (43, 44), we assessed whether HC and MS-derived TIM-1+ or DP memB cells induced increased expression of IL-10 in direct accordance with the levels of induced pro-inflammatory IFNγ or IL-17 (Figure 2D). The gene discussed is RND3; the disease is myeloid sarcoma.