IFIH1 and interstitial lung disease: However, in further multivariate regression analysis with the adjustment of other covariates, only age > 43.5 years [HR: 7.653 (95% CI: 2.005-29.204), p = 0.003], absolute NK cell count < 148 cells/μL [HR: 6.277 (95% CI: 1.572-25.067), p = 0.009] and Th cells < 533.2 cells/μL [HR: 4.703 (95% CI: 1.014-21.821), p = 0.048] remained significant independent predictors of PF-ILD in patients with anti-MDA5+ DM.