TLR4 and bronchopulmonary dysplasia: Given the role of TLR4/NF-κB signaling pathway in inflammation, we investigated the beneficial effect of inhaled H2 on LPS-induced BPD, and we raised the question: does hydrogen inhibit inflammation by downregulating the expression of the hub protein TLR4 and subsequently reducing the activity of the NF-κB-mediated inflammatory signaling pathway?