Given the fact that the STAT family members could be activated by the MET, a well-known receptor tyrosine kinase [47], and the elevated expression of MET has been reported in various cancers including PCa [48–50], we herein wondered whether phosphorylation of MET can activate STAT5A [51, 52] for promotion of NE trans-differentiation [53]. This evidence concerns the gene SOAT1 and posterior cortical atrophy.