Notably, analysis of tumor cell composition indicated eradication of CD19+ tumor cells after transfer of CAR T cells, consistent with tumor control as measured by size (Fig. 7C), but not after ACT of any of the other effector cells, including CAR NK cells, as CD19+ cells were distinctly depleted only in tumors of mice receiving CAR T cells (Fig. 7E). This evidence concerns the gene CD19 and neoplasm.