IL6 and allergic disease: Allergic sensitization or exacerbation of allergic diseases was associated with interleukin (IL)-6 and activation of toll-like receptors (TLR) 2 and TLR 4, which can promote T helper type 2 (Th2) differentiation, stimulation of these receptors, and subsequent cytokines released, and may further impair glucose homeostasis [27, 28].