IL-1, IL-6, IL-7/IL-7R, IL-8, IL-17, TGFs, and TNFs, as well as CXCL1–CXCL6, and CXCL8–CXCL16, all play important roles in PCa inflammatory response, metastatic spread, angiogenesis, progression, and development. The gene discussed is IL1A; the disease is posterior cortical atrophy.