IL-1, IL-6, IL-7/IL-7R, IL-8, IL-17, TGFs, and TNFs, as well as CXCL1–CXCL6, and CXCL8–CXCL16, all play important roles in PCa inflammatory response, metastatic spread, angiogenesis, progression, and development. This evidence concerns the gene CXCL6 and posterior cortical atrophy.