However, they significantly differed in terms of marker genes (AKR1C1, FOSL1, LIF, and THAP2 vs. WNT5A, GREM1, TNC, and MMP1), tissue origins (normal vs. tumor), and organ preferences (Figs. 3E, 4A, B, and Supplementary Fig. S12B, C). This evidence concerns the gene LIF and neoplasm.