However, they significantly differed in terms of marker genes (AKR1C1, FOSL1, LIF, and THAP2 vs. WNT5A, GREM1, TNC, and MMP1), tissue origins (normal vs. tumor), and organ preferences (Figs. 3E, 4A, B, and Supplementary Fig. S12B, C). The gene discussed is TNC; the disease is neoplasm.