PRF1 and neoplasm: Corresponding to their multiple targeting mechanisms (Fig. 2f–, l) and strong cytotoxic functions (Fig. 1j), Allo15BCAR-NKT cells displayed superior tumor cell killing efficacy compared with BCAR-T cells against both primary patient samples (Fig. 2e) and tumor cell lines (Fig. 2i), which was associated with upregulation of activation markers (that is, CD69) and production of cytotoxic molecules (that is, Perforin and Granzyme B) and effector cytokines (that is, IFNγ) (Fig. 2m,n and Supplementary Fig. 7g,, h).