Treatment with Allo15BCAR-NKT cells, but not BCAR-T cells, effectively depleted this CRS-related macrophage population in the BM (Fig. 5j,k,n) and reduced CRS-related biomarker (that is, IL-6 and SAA-3) measurements in the serum (Fig. 5p,q)59,60. The gene discussed is SAA3P; the disease is congenital rubella syndrome.